The anime centers on Manatsu, who moves from her small island birthplace to a city and starts middle school. On the day she moves she meets a mermaid girl named Laura who is looking for the "legendary warriors," the Precures. Laura's hometown, the mermaid country of Grand Ocean, has been attacked by the "procrastination witch," who has stolen the country's "motivation power." (Source: ANN)

Professor Senbei finds a videotape of his deceased father providing instructions on how to create a love potion. The main ingredient is a tear of the evil Gyaasuka Daimao who lives at the Wonder Island. To retrieve it, Senbei takes Arale and Gatchan on a wacky adventure. (Source: ANN)

Arale and her friends learn of a World Grand Prix being organised by the Radial Kingdom. The prize is marrying Princess Front (a dead ringer to Ms. Yamabuki) or 1 million dollars. Of course they decide to enter for the money. Not so for Dr. Mashirito; he is going for the princess and will stop at nothing to win! The princess though has her own plan, which involves Ms. Yamabuki, and that of course means even Dr. Slump decides to enter with his trusty Borobo. Let the race begin... (Source: M74)

Dr. Slump found the secret treasure named “Eye of Rainbow” of legendary Nanaba Castle in the mountain. This treasure makes every dream come true. When the robbery gang of Arale, Ga-chan tried to steal this treasure, Bisna who is the descendant of Nanaba Kingdom took the treasure. Bisna wanted to revive the devil and Nanaba Kingdom. Arale and her friends went towards the secret Nanaba Castle to get back the treasure. (Source: Official Website)