A deadly virus known as "Algernon" has attacked humanity with vicious meaning. At the forefront of the battle is the mystifying Akamatsu Industries—disguised as a heavy machine factory in Tokyo, this undercover organization uses neural enhanced weapons known as NeuroNoids to battle Algernon. Also helping with their secret efforts is the mysterious mutant who is only known as "Betterman." (Source: ANN)

Ceres was a tennyo (Celestial maiden) who came down from the heavens to bathe in a stream. She hung her hagoromo (robe) on a tree nearby, which was her key to returning to the heavens. But the robe was stolen and the man who had stolen it forced her to become his wife, thus producing a family full of human and tennyo blood mixed. Now, in modern day time, Aya Mikage is a descendent of Ceres, and has quite an amount of tennyo blood. On her 16th birthday, she and her twin brother, Aki, are thrown a party. At the "party," Aya's grandpa plans to kill her, for she has tennyo powers unlike the rest of the family, and can actually become Ceres herself and destroy the Mikage family. Aya, however, can switch back, so this transformation happens quite frequently. With protector Yuuhi by her side, it is up to Aya to control Ceres and keep her from coming back, but her relationship with an ex-worker for her evil grandpa may be a distraction.

A series of gruesome murders dubbed "New Generation Madness" once induced mass hysteria in Shibuya. At its peak during a frenzied riot, a sudden earthquake reduced the district into nothing but rubble, while leaving surrounding wards strangely intact. Six years later, in a newly rebuilt Shibuya, mysterious deaths begin to crop up again. It is not long before third-year student Takuru Miyashiro realizes a connection: the dates of the recent murders match those of the New Generation Madness incidents. He, along with several members of his school's newspaper club, decide to delve deeper into the mystery, only to find themselves stranded in the middle of a new crime scene themselves... [Written by MAL Rewrite]

In a distant future, Earth has become a wasteland and humanity as we know it has died out. All that remains are sentient robots. They were supposed to be able to live forever—until the one called Luna died and The Ruin started. Their bodies will rust, and there is nothing that can be done to fix it. Now the robots are left only to contemplate their deaths, kept going only by the rumor that if they eat the one called Casshern they will gain immortality. Casshern knows nothing about his past, why he exists or what he is, but he must find out or he will face the constant torment of being hunted by robots who don't want to die. Casshern leaves death wherever he goes, but he must face it if he is to find out the truth of this world. [Written by MAL Rewrite]