The 7th Division's Private Hyakunosuke Ogata and former Shinsengumi Vice Commander Toshizou Hijikata find themselves on opposite sides of a gang war in Barato after hearing rumors of the Hidoro gang possessing an escaped prisoner's tattooed skin. With a lead to the hidden Ainu gold close at hand, the two gladly take up arms but a betrayal will force both sides to think twice before carelessly jumping the gun.

The story revolves around Nikolai, apparently a part-cyborg; Galory, a young boy who apparently is part human/part Crest person, and Althea, who is entirely a Crest person. Seems the Earth and the Crest people were at war for 300 years so there's still a lot of bad feelings present. The ship Galory, Nikolai and others are on is ambushed and almost everyone killed by some kind of automated attack ships from a huge Crest ship that has been taken over by an automaton. Galory, Nikolai and Althea go to the ship to try and see if there are any survivors of an advanced party from Galory's ship that can be saved, and to see if they can destroy the Type 38 automaton in the ship's core.

In My Hero Academia: World Heroes’ Mission, a mysterious terrorist group called the Humanize are introduced. They strongly believe in the "Quirk Singularity Doomsday Theory." The theory states that as future generations continue to be mixed with the Quirk genes, the power it holds will lead to humanity’s demise. Furthermore, Humanize believes that Quirks are a disease, and so, they plan to “cleanse the world” by exterminating anyone who has one. Humanize planted "Ideo Trigger Bombs" in various countries, and these explosives are said to make a Quirk-user lose control of their Quirk, leading to mass destruction. To save and protect everyone, Pro-Heroes from around the world, and the U.A. Academy heroes-in-training, unite to thwart the efforts of the mysterious group.

After the defeat of Myouri Unzen at the hands of Medaka Kurokami and her Student Council, peace has returned to Hakoniwa Academy—at least, for a short while. Soon, Medaka, Zenkichi Hitoyoshi, Kouki Akune, and Mogana Kikaijima find themselves wrapped up in another sinister scheme, known as the "Flask Plan," led by the school's principal himself. However, the council's first problem is to deal with a whole new group of superhuman students calling themselves the "Thirteen Party," led by the egotistical but powerful Oudo Miyakonojou. With the mysterious Flask Plan, Oudo's tyranny, and the resurfacing of an old enemy, the state of Hakoniwa Academy is far from tranquil, and Medaka and her companions have their hands full as things only get a lot more abnormal. [Written by MAL Rewrite]